Causes of infertility
Basic Outlines
for Women.
1 / Ovulation Disorders
This happens to be the most common cause of infertility in women. As explained on the previous page, ovulation is the release of an egg from the ovaries. Often, in the case of infertility, eggs are never released, or are released infrequently. There are many problems that can lead to ovulation disorders, such as the misregulation of hormones in the body, or specific problems in the ovaries. Other causes can be thyroid problems or chronic conditions.
2 / Pcos
PCOS, or Polycystic Ovary Syndrome can cause imbalances in reproductive hormones. PCOS has unrecognizable symptoms, such as obesity, abnormal hair growth and acne. These means that it can go undetected for long periods of time.
PREMATURE OVARIAN FAILURE: Also known as premature menopause, is when the ovaries stop working before the age of 40 years. This is often caused by an autoimmune response, or by premature loss of eggs for ovaries, due to causes like exposure to radiation, or genetics.
HYPERPROLACTEINEMIA: This is due to high prolactine levels, even though the woman is not pregnant or breastfeeding. This can be due to the pituitary gland producing too much prolactin, which in turn reduces estrogen production. This can be due to medication intake to treat another disease.
3 / Hypothalmic Dysfunction
The pituitary gland is responsible for producing two hormones, which both aid in simulating ovulation. One is Follicle-Stimulating Hormone, or FSH, and the second is luteinizing hormone, or LH. External factors like extreme BMIs, physical or emotional stress, weight gain or weight loss can all create jolts in hormone production and affect ovulation. A tell a tale sign of this can be irregular periods.
4 / Tubal Blockage
Damaged fallopian tubes, from endometriosis or STIs can keep the sperm from reaching the egg, or block the fertilized egg from getting implanted into the uterus wall. Other reasons of tubal blockage can be from scarring from pelvic tuberculosis, or from previous surgery in the abdomen or pelvis.
5 / Uterine Fibroids or Polyps
Benign uterine fibroids are common in the uterus. These often tend to block fallopian tubes, or might interfere with implantations. However, it should be noted that women with uterine fibroids to end up pregnant.
6 / Poor Ovarian Reserve
This is due to when the ovaries have a lower existing reserve of eggs, which reduces the chances of fertilization. This could be caused by genetics, environmental factors, exposure to chemicals and radiations, smoking etc.
7 / Genetic Factors
Uterine abnormalities that have been present from birth, due to genes passed down from a woman’s mother, can often affect fertility. Other genetic factors that could affect the uterus include cervical stenosis, which causes the narrowing of the cervix. A similar problem might be a situation wherein the cervix is unable to produce enough mucus to sustain sperm to pass into the uterus. As previously mentioned, poor ovarian reserve can also be used to this.
8 / Endometriosis
Endometriosis occurs when endometrial tissue grows outside the uterus. This tends to affect the function of the ovaries, uterus and fallopian tubes. Endometriosis disrupts the implant The surgical removal of this can cause scarring, which can also block fallopian tubes.
9 / Unexplained
Sometimes, the cause(s) of infertility is never found, as there is a chance that infertility may be due to a combination of several insignificant factors from both partners. However, sometimes, with persistent treatment, and a careful lifestyle, the problem may correct itself.
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Our Expert
Dr. Lakshmi Chirumamilla

Dr. Lakshmi Chirumamilla is a distinguished Infertility Specialist and Reproductive Endocrinologist with over 25 years of expertise in Gynaecology and Reproductive Medicine. She holds an M.D. (OBG), FRCOG (London, UK), and DFSRH (UK). She has completed a Fellowship in Assisted Conception at the Royal Infirmary, Edinburgh, UK, as well as a Fellowship in Reproductive Endocrinology at St. George’s Hospital, London, UK.
She has also completed her Fellowship in Infertility and Assisted Reproduction (IVF) at these prestigious institutions. Additionally, Dr. Lakshmi earned the prestigious ‘Special Skills Module’ certification in Assisted Reproduction and Infertility from the Royal College of Obstetricians and Gynaecologists and the British Fertility Society.
25+ years of experience
Internationally Trained. With experience spanning across the UK, and Hyderabad. 8000+ Couples Treated.
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With her technique of personalising treatments per patient, to include lifestyle factors too, Dr. Lakshmi's success rate exceeds the industry standards by miles
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Believes that testing, treatments and medication should only be used where necessary.
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With options including minimally invasive natural conception, treating male infertility, IUI, IVF, Fertility Preservation, 3rd party reproduction.
